Events
Births
- January 1 - Henry, Duke of Cornwall, eldest son of Henry VIII of England
- July 3 - Giorgio Vasari, Italian painter and architect (died 1574)
- September 29 - Michael Servetus, theologian (died 1553)
- October 22 - Erasmus Reinhold, German astronomer and mathematician (died 1553)
- November 15 - Johannes Secundus, Dutch poet (died 1536)
- Bartolomeo Ammanati, Florentine architect and sculptor (died 1592)
- Nicholas Bobadilla, one of the first Jesuits (died 1590)
- Dorothea of Saxe-Lauenburg, consort of Christian III from 1525 and Queen of Denmark and Norway (died 1571)
- Kimotsuki Kanetsugu, Japanese samurai and warlord (died 1566)
- Amato Lusitano, Portuguese Jewish physician (died 1568)
- Ippolito de' Medici, illegitimate only son of Cardinal Giuliano de' Medici (died 1535)
- Nicola Vicentino, Italian music theorist and composer (died 1576)
- Pierre Viret, Swiss reformed theologian (died 1571)
Deaths
- February 11 - Henry, Duke of Cornwall, eldest son of Henry VIII of England
- September 6 - Ashikaga Yoshizumi, Japanese shogun (born 1481)
- Andrew Barton, Scottish privateer
- La Beata de Piedrahita, Spanish mystic
- Demetrius Chalcondyles, Greek classical scholar (born 1424)
- Philippe de Commines, French-speaking Fleming in the courts of Burgundy and France (born 1447)
- Antoine de Févin, French composer (born 1470)
- Diego de Nicuesa, Spanish conquistador and explorer
- Matthias Ringmann, German cartographer and humanist poet (born 1482)
- Johannes Tinctoris, Flemish composer and music theorist (born 1435)
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